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Industry PhD in Computational Protein Design

Ansök    Maj 24    Cytiva Sweden AB    Doktorand
We are looking for a motivated PhD student to join us in a unique, collaborative project between our Affinity Ligand Design team at Cytiva and the Elofsson group at Stockholm University, where we will use machine learning methods to develop affinity ligands. These methods have been transformative for protein design, allowing generation of novel proteins which can suit a precise need. In this 4 year project, funded by the DDLS program, we aim to develop AI-... Visa mer
We are looking for a motivated PhD student to join us in a unique, collaborative project between our Affinity Ligand Design team at Cytiva and the Elofsson group at Stockholm University, where we will use machine learning methods to develop affinity ligands. These methods have been transformative for protein design, allowing generation of novel proteins which can suit a precise need. In this 4 year project, funded by the DDLS program, we aim to develop AI-based tools in design of affinity ligands, such as the prediction of binding interactions between proteins.
Data-driven life science (DDLS) uses data, computational methods and artificial intelligence to study biological systems and processes at all levels, from molecular structures and cellular processes to human health and global ecosystems. The SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS) aims to recruit and train the next generation of data-driven life scientists and to create globally leading computational and data science capabilities in Sweden. The program is funded with a total of 3.3 billion SEK over 12 years from the Knut and Alice Wallenberg (KAW) Foundation.
In 2025, the DDLS Research School will be expanded with the recruitment of 19 academic and 7 industrial PhD students. During the course of the DDLS program more than 260 PhD students and 200 postdocs will be part of the Research School. The DDLS program has four strategic research areas: cell and molecular biology, evolution and biodiversity, precision medicine and diagnostics, epidemiology and biology of infection. For more information, please see https://www.scilifelab.se/data-driven/ddls-research-school/ The future of life science is data-driven. Will you be part of that change? Then join us in this unique program!
The Elofsson group is located at the Science for Life Laboratory. Elofsson has worked on protein structure predictions for more than two decades and on various techniques using machine learning and other computational techniques. Some of his most important contributions to this work are the methods he has developed to improve the prediction of membrane protein, protein structures and protein interactions. The group comprises four PhD students, one postdoc, and one senior researcher. For recent publications, see here: https://archive.bioinfo.se/papers/
Cytiva’s Affinity Ligand Design team is a small unit of our company, located in the Karolinska campus, and is responsible for discovering and designing new affinity purification ligands and solutions for the next generation of biopharmaceuticals. We consist of about 15 experts in the field of protein engineering, protein production, affinity ligand design and characterization, and machine learning for protein design.
This unique PhD position is a 4-year collaborative project where you will work at the Cytiva Solna and Elofsson lab environments, both located at the Solna Campus. Upon successfully completing the 4-year project, you will obtain a PhD in Bioinformatics from Stockholm University.
Requirements:
An MSc, including a thesis of at least 30 hp in Biotechnology, Bioinformatics, or related fields.
English as a working language, with Swedish as a strong merit.
Experience in Python programming.
Experience with machine learning methods, bioinformatics, and data science.
Familiarity with generative AI tools for protein design and protein language models.
Knowledge of protein structure, function, and interactions.
It is a merit if you have knowledge of protein engineering, characterization and/or purification methods.
A valid EU work permit is required.

Please submit your application no later than June 29th. For questions regarding the role, please contact Professor Arne Elofsson at [email protected] or the Project Manager at Cytiva, Sarah McComas at [email protected].
Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
For more information, visit www.danaher.com.
At Danaher, we value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes. Visa mindre

Scientist, Protein Engineering

Be part of something altogether life-changing Working at Cytiva in the Life Sciences industry means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies. At Cytiva you will be able to continuously improve yourself and us –working on challenges that truly ... Visa mer
Be part of something altogether life-changing
Working at Cytiva in the Life Sciences industry means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.
At Cytiva you will be able to continuously improve yourself and us –working on challenges that truly matter with people that care for each other, our customers, and their patients. With associates across 40 countries, Cytiva is a place where every day is a learning opportunity –so you can grow your career and expand your skills in the long term.
Cytiva is proud to work alongside a community of nine fellow Danaher Life Sciences companies. Together, we’re pioneering the future of science and medicine, developing products that enable researchers in the fight to save lives.
We are looking for a Scientist in the area of protein engineering and affinity ligand discovery to join the Affinity Ligand Design team in our lab in Solna, Stockholm. The team is responsible for discovering and designing new affinity purification ligands and solutions for the next generation of biopharmaceuticals and consists of about 15 experts in the field of protein engineering, protein production, affinity ligand design and characterization. The primary focus of this position is the design, identification and engineering of novel affinity ligands as well as the design of novel protein scaffolds and libraries.
In this role, you will have the opportunity to:
Design and create new affinity ligand libraries based on various protein scaffolds.
Discover and isolate new affinity ligands using various techniques and improve/mature the stability and affinity of affinity ligands.
Determine the affinity, stability and specificity of the ligands using different methods such as Biacore and flow cytometry.
Participate in ligand development projects and contribute within the area of expertise.
Depending on project needs act as an activity leader.
Present scientific and technical results internally and externally, oral and written communication in Swedish and English.

The essential requirements of the job include:
PhD in biotechnology, biochemistry, engineering, or related Life Science field and preferably industrial experience or a post doc within the field of protein or antibody engineering.
You have hands on experience of one or more protein engineering techniques such as protein library creation, phage display, antibody engineering, yeast or bacterial display.
English and Swedish as working languages.

It would be a plus if you also possess previous experience in:
Background in computational biology.
Python programming experience.
Additional experience of analytical methods such Biacore and ELISA.
Hands on experience working with protein purification and characterization.

This position will be open to applications over the holiday season (June-July), and we expect to initiate selection of candidates and interviews in August. For questions regarding the role, please contact Tobias Cornvik, Section Manager Bioprocess Applications, [email protected].
At Danaher we bring together science, technology and operational capabilities to accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life. Our global teams are pioneering what’s next across Life Sciences, Diagnostics, Biotechnology and beyond. For more information, visit www.danaher.com.
At Danaher, we value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes. Visa mindre

Research Engineer - Protein engineering and characterization

Be part of something altogether life-changing Working at Cytiva in the Life Sciences industry means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies. At Cytiva you will be able to continuously improve yourself and us – working on challenges that truly... Visa mer
Be part of something altogether life-changing
Working at Cytiva in the Life Sciences industry means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.
At Cytiva you will be able to continuously improve yourself and us – working on challenges that truly matter with people that care for each other, our customers, and their patients. With associates across 40 countries, Cytiva is a place where every day is a learning opportunity – so you can grow your career and expand your skills in the long term.
Cytiva is proud to work alongside a community of nine fellow Danaher Life Sciences companies. Together, we’re pioneering the future of science and medicine, developing products that enable researchers in the fight to save lives.
We are looking for a Research Engineer in the area of protein engineering / molecular biology to join the Affinity Ligand Design team in our new lab in Stockholm as part of the expansion of our affinity ligand programs. The Affinity Ligand Design team is responsible for discovering and designing new affinity purification ligands and solutions for the next generation of biopharmaceuticals and consists of about 15 experts in the field of protein engineering, protein production, affinity ligand design and characterization. The primary focus of this position is to plan and perform protein engineering and molecular biology experiments as part of a team developing new affinity ligands.
What you’ll do:
Design and create new affinity ligand libraries based on various protein scaffolds.
Discover and isolate new affinity ligands using various techniques.
Improve/mature the stability and affinity of affinity ligands.
Determine the affinity, stability and specificity of the ligands using different methods such as Biacore and flow cytometry.
Present scientific and technical results internally and externally, oral and written communication in Swedish and English.

The essential requirements of the job include:
MSc or equivalent experience in biology, biochemistry, engineering or related Life Science field.
A few years’ experience in the field of molecular biology, protein chemistry or protein characterization.
Sound knowledge of various molecular biology methods and phage display or other protein engineering techniques.
English and Swedish as working languages.

It would be a plus if you also possess previous experience in:
Additional experience of methods used in protein characterization such as Biacore is desirable.
Experience working in the Life Science industry.

To be successful in the role as Research Engineer we believe that you're a results-oriented, flexible and creative individual with a strong collaborative attitude and excellent interpersonal skills.
Interview and selection will happen continuously and the opening can be filled before last day of application, April 14th. For questions regarding the role please contact hiring manager Tobias Cornvik at [email protected].
At Danaher we bring together science, technology and operational capabilities to accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life. Our global teams are pioneering what’s next across Life Sciences, Diagnostics, Biotechnology and beyond. For more information, visit www.danaher.com.
At Danaher, we value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes. Visa mindre

Scientist, Protein Design / Computational Biology

Ansök    Apr 2    Cytiva Sweden AB    Forskare, bioteknik
Be part of something altogether life-changing Working at Cytiva in the Life Sciences industry means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies. At Cytiva you will be able to continuously improve yourself and us –working on challenges that truly ... Visa mer
Be part of something altogether life-changing
Working at Cytiva in the Life Sciences industry means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.
At Cytiva you will be able to continuously improve yourself and us –working on challenges that truly matter with people that care for each other, our customers, and their patients. With associates across 40 countries, Cytiva is a place where every day is a learning opportunity –so you can grow your career and expand your skills in the long term.
Cytiva is proud to work alongside a community of nine fellow Danaher Life Sciences companies. Together, we’re pioneering the future of science and medicine, developing products that enable researchers in the fight to save lives.
We are looking for a Scientist in the area of protein design and computational biology to join the Affinity Ligand Design team in our new lab facilities in Solna, Stockholm. The Affinity Ligand Design team is responsible for discovering and designing new affinity purification ligands and solutions for the next generation of biopharmaceuticals and consists of about 15 experts in the field of protein engineering, protein production, affinity ligand design and characterization. The focus of the positions is to work as a bridge/translator between our molecular biologist/protein engineering team and our data scientist as well as setting up new AI/ML models for protein design. You will also be an active part of projects that design, identify and engineer novel affinity ligands using both wet lab and in silico approaches.
What you’ll do
Act as a bridge/translator between our molecular biologist/protein engineering team.
Implement new AI/ML models for protein design.
Discover and isolate new affinity ligands using various techniques, using both wet lab-based approaches as well as in silico based ones.
Participate in ligand development projects and contribute within the area of expertise.
Present scientific and technical results internally and externally, oral and written communication in both Swedish and English.

Who you are
PhD in biotechnology, structural biology, bioinformatics or related Life Science field and preferably industrial experience or a post doc within the field of protein / antibody engineering or computational biology.
You are familiar with one or more protein engineering techniques such as protein library creation, phage display, antibody engineering as well as state of the art generative AI tool for protein design, e.g. RFdiffusion & ProteinMPNN, protein language models such as ESM2.
Experience of programming in Python is a strong merit.
English and Swedish as working languages.



Interview and selection will happen continuously and the opening can be filled before last day of application. For questions regarding the role please contact hiring manager Tobias Cornvik at [email protected]. We look forward to hearing from you! Visa mindre

Scientist, Protein Engineering

Ansök    Dec 6    Cytiva Sweden AB    Biokemist
Be part of something altogether life-changing Working at Cytiva in the Life Sciences industry means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies. At Cytiva you will be able to continuously improve yourself and us –working on challenges that truly ... Visa mer
Be part of something altogether life-changing
Working at Cytiva in the Life Sciences industry means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.
At Cytiva you will be able to continuously improve yourself and us –working on challenges that truly matter with people that care for each other, our customers, and their patients. With associates across 40 countries, Cytiva is a place where every day is a learning opportunity –so you can grow your career and expand your skills in the long term.
Cytiva is proud to work alongside a community of nine fellow Danaher Life Sciences companies. Together, we’re pioneering the future of science and medicine, developing products that enable researchers in the fight to save lives.
We are looking for a Scientists/Senior Scientists in the area of protein engineering and affinity ligand discovery to join the Affinity Ligand Design team in our new lab that is being established in Solna, Stockholm as part of the expansion of our affinity ligand programs. The team is responsible for discovering and designing new affinity purification ligands and solutions for the next generation of biopharmaceuticals and consists of about 15 experts in the field of protein engineering, protein production, affinity ligand design and characterization. The primary focus of these positions are the design, identification and engineering of novel affinity ligands as well as the design of novel protein scaffolds and libraries.
In this role, you will have the opportunity to:
Design and create new affinity ligand libraries based on various protein scaffolds.
Discover and isolate new affinity ligands using various techniques and improve/mature the stability and affinity of affinity ligands.
Determine the affinity, stability and specificity of the ligands using different methods such as Biacore and flow cytometry.
Participate in ligand development projects and contribute within the area of expertise.
Depending on project needs act as an activity leader.
Present scientific and technical results internally and externally, oral and written communication in Swedish and English.

The essential requirements of the job include:
PhD in biotechnology, biochemistry, engineering, or related Life Science field and preferably industrial experience or a post doc within the field of protein or antibody engineering.
You have hands on experience of one or more protein engineering techniques such as protein library creation, phage display, antibody engineering, yeast or bacterial display.
English and Swedish as working languages.

It would be a plus if you also possess previous experience in:
Additional experience of analytical methods such Biacore and ELISA.
Hands on experience working with protein purification and characterization.

Interview and selection will happen continuously and the opening can be filled before last day of application, December 31st.
When you join us, you’ll also be joining Danaher’s global organization, where 69,000 people wake up every day determined to help our customers win. As an associate, you’ll try new things, work hard, and advance your skills with guidance from dedicated leaders, all with the support of powerful Danaher Business System tools and the stability of a tested organization.
At Danaher, we value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.
If you’ve ever wondered what’s within you, there’s no better time to find out. Visa mindre